Criteria for Application of Therapy
Immunotherapy is personalized according to the patient’s characteristics and pathology.
Candidates for Therapy
Every cancer patient is a candidate for NK cell immunotherapy
Given the mechanism of action of NK cells, individuals with non-solid tumors have reported
a higher rate of effectiveness, including complete remission.
It can be applied in conjunction with other pharmacological or cellular therapies.
- A 24-hour window is suggested between each of the therapies.
- If at least 24 hours are not available, apply therapies with the greatest difference in hours available
The use of chemo or radiation therapy is not recommended within the first week before or after the use of Natural Killer.
Safety and Quality of the doses
Our cells are obtained from leukocyte concentrates from healthy donors
- Brucella. – Negativo
- T. cruzi – Negativo
- Hepatitis C – Negativo
- Hepatitis B – Negativo
- HIV – Negativo
- Sifilis – Negativo
Cells grown in the laboratory are evaluated by flow cytometry to ensure:
- Purity (NK population only)
- Safety (no T or B lymphocytes that
- could cause adverse effects)
- Quality (Mature CD16+ cells)
- Efficiency (Cytotoxic CD16+ and active NKG2D+ population)
Activation and Action Time
Like all cells of the immune system, NK cells have specific and perfectly defined kinetics of activation and elimination of tumors.
For this reason, its application is recommended within the first hours after dosing in the laboratory.
probabilidad de identificar mediante análisis geneticos la presencia de células no propias es nula
Applications and dosage
The recommended management will be established according to the pathology and condition of the patient.
Suggested minimum dose: 1 million cells/kg
Suggested minimum applications: 3 applications
Application frequency: 7 or 15 days as possible
Route of administration: Intravenous and intratumoral
Adverse effects
- Low-grade fever
- Headache
All symptoms disappear within a period of no more than 24 hours, and/or can be controlled with over-the-counter analgesics and antipyretics.
